A man, John Murdoch wakes up in the bath of his hotel room, with no memory, not even of his name, and a dead prostitute in the room. He receives a phone call from Doctor Schreber, telling him that some people are coming for him and he should leave immediately. He flees, becoming the prime suspect in a series of murders of prostitutes. On the case is Inspector Frank Bumstead, who's intrigued when Murdoch's wife, Emma, reports him missing. Meanwhile, it is clear that some strange people with special powers are after Murdoch...—grantss