A grizzly bear named Boog (Martin Lawrence), domesticated by Park Ranger Beth (Debra Messing), helps deer friend Elliot (Ashton Kutcher) escape from the mullet-sporting hunter, Shaw (Gary Sinise). When Elliot decides to return the favor to help Boog escape from Beth, he finds that Boog is very happy with his domesticated home. After a misunderstanding, Beth is convinced that Boog is reverting to his wild nature and releases him in the woods just as hunting season begins. Boog has no idea how to survive outside of his garage home with his beloved Beth. Elliot and Boog develop a strong bond not only between themselves but also with the wild animals and attempt to drive the hunters out of the forest.